Lab members Ibolya Leveles and Kinga Nyíri visit the BESSY synchrotron
In this week two members of our group (Ibolya Leveles and Kinga Nyíri) are visiting Helmholtz-Zentrum Berlin for measuring X-ray diffraction data of crystals from various projects, using sincrotron radiation of BESSY II. Hopefully they will come home with many valuable datasets recorded during the eight-hours shift.
New article published in FEBS Journal
Our paper entitled "Preventive DNA repair by sanitizing the cellular nucleotide triphosphate pool" has been published in FEBS Journal.
The molecular mechanism of substrate coordination and catalysis of enzymes removing unwanted nucleotides from the dNTP pool constitutes the long-standing interest of our research group. The review provides a comparative summary of structural and mechanistic novelties of housekeeping dNTP pyrophosphatase enzymes. dNTP PPase enzymes are organized into two main groups, depending on their catalytic mechanisms, featured by the nucleophilic attack centered on the α-phosphate or β-phosphate of the cognate nucleotide substrate. Revisiting the available biochemical and structural data enabled us to reveal characteristic differences between these two groups of enzymes has been highlighted that include coordination of the γ-phosphate of the substrate,the divalent metal cation, and the catalytic water nucleophile.
(FEBS Journal, 18 Aug 2014, DOI.: 10.1111/febs.12941)
News articles on the Metagenomic Telescope
Our paper “The Metagenomic Telescope” received widespread online coverage among Hungarian news sites. Below is a selection of the news articles concerning the Telescope.
- http://nemzeti.net/magyar-teleszkop-segit-a-feherjekutatasban-2274520.html or cached version
- http://kozpontban.hu/blog/uj-magyar-bioinformatikai-eszkoz-segit-felderiteni-feherjek-mukodeset/ or cached version
- http://biokalauz.hu/cikk/id/uj_magyar_bioinformatikai_eszkoz_segit_felderiteni_a_feherjek_mukodeset_290714or cached version
- http://elteonline.hu/rovidhirek/2014/08/01/teleszkop-a-feherjekhez/ or cached version
- http://profitline.hu/hircentrum/hir/315897/Uj-magyar-bioinformatikai-eszkoz-segit-felderiteni-a-feherjek-mukodeset or cached version
- http://www.radiosom.hu/index.php/hirek/5407-uj-magyar-bioinformatikai-eszkoez.html or cached version
- http://blog.otka.hu/2014/07/30/magyar-kutatok-a-feherjek-mukodesenek-nyomaban/ or cached version
- http://www.hirado.hu/2014/07/29/uj-magyar-bioinformatikai-eszkozzel-deritik-fel-a-feherjek-mukodeset/ orcached version
- http://www.ttk.mta.hu/2014/07/egyedulallo-eszkozt-fejlesztettek-magyar-kutatok/ or cached version
- http://www.gyartastrend.hu/cikk/ismeretlen_mukodesi_formakat_kutatnak or cached version
- http://veddamagyart.info/tudomany/7266-uj-magyar-bioinformatikai-eszkoz-segit-felderiteni-a-feherjek-mukodeset or cached version
- http://mno.hu/tudomany/magyar-teleszkop-segit-a-feherjekutatasban-1239689 or cached version
- http://www.havasok.hu/cikk/uj-magyar-bioinformatikai-eszkoz-segit-felderiteni-a-feherjek-mukodeset orcached version
- http://www.mon.hu/uj-magyar-bioinformatikai-eszkoz-segit-felderiteni-a-feherjek-mukodeset/2607076?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+mon%2Forszagos+%28Magyar+Online+Orsz%C3%A1gos%29 or cached version
- http://www.boon.hu/uj-magyar-bioinformatikai-eszkoz-segit-felderiteni-a-feherjek-mukodeset/2607076?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+boon%2Forszagos+%28Borsod+Online+Orszagos+H%C3%ADrek%29 or cached version
- http://szegedma.hu/hir/szeged/2014/07/uj-magyar-bioinformatikai-eszkoz-segit-felderiteni-a-feherjek-mukodeset.html or cached version
- http://magyarhirlap.hu/cikk/1748/Uj_magyar_eszkoz_segit_felderiteni_a_feherjek_mukodeset or cached version
- http://biokalauz.hu/?/a/cikk/id/uj_magyar_bioinformatikai_eszkoz_segit_felderiteni_a_feherjek_mukodeset_290714 or cached version
- http://hvg.hu/instant_tudomany/20140728_Egyedulallo_eszkozt_fejlesztettek_magyar or cached version
- http://index.hu/tudomany/2014/07/28/magyarok_kutatjak_a_feherjek_ismeretlen_oldalat/ or cached version
- http://www.weborvos.hu/hirek/egyedulallo_eszkozt_fejlesztettek_magyar_kutatok/216142/ or cached version
- http://www.nyest.hu/hirek/egyedulallo-eszkozt-fejlesztettek-magyar-kutatok or cached version
- http://www.ma.hu/eletmod.hu/220513/Miert_erdemes_kutatni_az_extrem_bakteriumokat or cached version
- http://www.mernokbazis.hu/cikkek/%C3%BAj-magyar-bioinformatikai-eszk%C3%B6z or cached version
- http://drinfo.hu/hirek/pubmed/21896-%C3%BAj-magyar-bioinformatikai-eszk%C3%B6z-seg%C3%ADt-felder%C3%ADteni-a-feh%C3%A9rj%C3%A9k-m%C5%B1k%C3%B6d%C3%A9s%C3%A9t or cached version
- http://jonapotkivanunk.hu/ujabb-magyar-talalmany/ or cached version
Lab running
On the move: lab members ran a maraton! The "Futprinting" team successfully participated at the 21st K&H maraton event.
(http://www.futanet.hu/cikk/21-maraton-es-felmaraton-valto/21-kh-esemenyinformacio)