• 2012_1.png
  • 2013_1.png
  • 2014_1.png
  • 2015_1.png

Beáta G. Vértessy

Personal:

DOB: 1961. 06. 15, Budapest, Hungary.

Marital status: married, two children (Vince, 1988, Viola, 1990)

 

Publication activities: over 90 peer-reviewed articles in international peer-reviewed scientific journals (in English, cf PubMed). Two book chapters, six patent applications, >200 other publications, >50 invited talks at international conferences.

H-index: 25, Independent citations: > 1000

Google Scholar 

 

Current areas of research: cellular trafficking, DNA repair, cell death pathways, cell biology, molecular and structural biology, molecular targets against tuberculosis and malaria

 

 

Education and Degrees

                                                                                                         

1979-1984 Budapest University of Technology, Hungary

Chemical Engineering and Bioengineering

 

Degree (1984) M. Sc. (summa cum laude) in Bioengineering 

Budapest University of Technology

                                                                                                         

1984-1987 Graduate fellowship, Hungarian Academy of Sciences

 

1986-1987 Graduate Studies, University of Chicago, USA 

Department of Biochemistry and Molecular Biology

 

Degree (1987) M.Sc. (summa cum laude) in Biochemistry and Molecular Biology 

University of Chicago

 

Degree (1991) Candidate of Biological Sciences (summa cum laude) 

Hungarian Academy of Sciences, Budapest, Hungary

 

Degree (1991) Ph. D. in Biological Sciences (summa cum laude)

Eötvös Loránd University, Budapest, Hungary

                       

Degree (2001) D. Sc. in Biological Sciences (defense 100%) 

Hungarian Academy of Sciences, Budapest, Hungary

 

 

 

 

Affiliation:

 

1987 - 1989    Scientific Research Associate, Institute of Enzymology, Hungarian Academy of Sciences

 

1989 - 1994    Scientific Researcher, Institute of Enzymology, Hungarian Academy of Sciences

 

1994 - 2001    Senior Scientific Researcher, Institute of Enzymology, Hungarian Academy of Sciences

 

2001 –present  Scientific Research Advisor (university equivalent: Full Professor)

                      Institute of Enzymology, Hungarian Academy of Sciences

 

2001 –present  Group Leader (PI) Genome metabolism and Repair Laboratory

                      Institute of Enzymology, Hungarian Academy of Sciences

 

2009 – 2011    Scientific Research Advisor (university equivalent: Full Professor)

                      Budapest University of Technology and Economics

                      Department of Applied Biotechnology and Food Sciences

 

2010 – 2012    Deputy Director

                      Institute of Enzymology, Hungarian Academy of Sciences

 

2011 – present  Full Professor

                       Budapest University of Technology and Economics,

                       Department of Applied Biotechnology and Food Sciences

 

 

Postdoctoral studies and long-term research stays:

1993-1994      Alexander von Humboldt postdoctoral fellowship. Dept. Biochemistry, University of Saarland, Germany

 

1994                Department of Biochemistry and Molecular Biology, Stockholm University, Sweden

 

1995                Department of Biochemistry, University of Lund, Sweden

 

1999                Department of Biochemistry and Molecular Biology, University of Chicago, USA

 

 

Selected Awards:

Apáczai Medal for best student, Apáczai Csere János High School, Budapest, Hungary, 1979

IAESTE undergraduate fellowship. Dept. Biochem. University of Groningen, 1983

Graduate fellowship, Hungarian Academy of Sciences 1984

University of Chicago graduate student fellowship, 1986

Alexander von Humboldt postdoctoral fellowship, 1993

Qualitas Biologica, 1. prize, Biol. Res. Ctr, Hung. Acad. Sci. 1997

Bolyai Research fellowship, Hung. Acad. Sci, 1998-2001

Scientia Europaea Award (Institute de France and Aventis): 2000

Howard Hughes International Research Scholar (Howard Hughes Medical Institutes, USA):

2001–2005 and 2006-2010

Qualitas Biologica, 1. prize, Biol. Res. Ctr, Hung. Acad. Sci. 2004

Wellcome Award (instrumental), 2007

Baross Gábor award (infrastructural, cf www.biostruct.org/biostruct), 2011

UNESCO-L’Oréal Award, 2012

 

Other forms of Scientific Recognition (selected):

Cover page illustration Vértessy et al (1998) FEBS Lett. 421:83-89.  

Editor-in-Chief, Current Protein and Peptide Science dUTPase Hot Topic Issue 2001

“Paper of the Week” award, Journal of Biological Chemistry, 2004

Editor of Central European Journal of Biology, 2006-  

Reviewer for e.g.: PNAS, J Biol Chem, Nucleic Acids Research, FEBS Letters, PLoS ONE

Academic Editor of PLoS ONE, 2011-, FEBS Open Bio 2012-

 

Participation in Scientific Bodies (selected):

Hungarian Biochemical Association: member from 1994, deputy secretary 2006-2010, general secretary from 2010

Hungarian Humboldt Association: member from 1994, deputy secretary from 1997

American Association for the Advancement of Science (AAAS), member from 2001

Doctoral Committee of Budapest University of Technology and Economics, member from 2005

Federation of European Biochemical Societies, Advanced Course Committee, elected member 2006-2010, Chair 2013-present

Hungarian Scientific Research Fund (OTKA), member of scientific review juries from 2005

Elected member for General Assembly of the Hungarian Academy of Sciences 2007 - 2013

Chair of the Hungarian Fulbright Board, 2012-present

 

Principal Investigator, (selected major grants only)

OTKA K 68229    2007-2011

OTKA NK 84008 2011-2015

OTKA CK 78646 2009-2012

(OTKA stands for the Hungarian Scientific Research Fund, www.otka.hu)

Howard Hughes Medical Institutes 2001-2005

Howard Hughes Medical Institutes 2006-2010 (renewal)

(The only female HHMI International Scholar in Hungary)

EU FP6-2003 Lifesci-Health srIN-SILICO N° 012127 2005-2007

EU FP6 Lifesci-Health SPINE2-Complexes LSHG-CT-2006-031220 2006-2009

(http://www.spine2.eu/partners/index.php)

EU FP7-INFRASTRUCTURES-2011-1 N° 283570 BioStruct-X 2011-2015

 

Major recent publications (selected)

 

Róna G, Borsos M, Ellis JJ, Mehdi AM, Christie M, Környei Z, Neubrandt M, Tóth J, Bozóky Z, Buday L, Madarász E, Bodén M, Kobe B, Vértessy BG.

Dynamics of re-constitution of the human nuclear proteome after cell division is regulated by NLS-adjacent phosphorylation.

Cell Cycle. 2014;13(22):3551-64.

 

Nagy GN, Marton L, Contet A, Ozohanics O, Ardelean LM, Révész A, Vékey K, Irimie FD, Vial H, Cerdan R, Vértessy BG.

Composite aromatic boxes for enzymatic transformations of quaternary ammonium substrates. Angew Chem Int Ed Engl. 2014 Dec 1;53(49):13471-6.

 

Szabó JE, Németh V, Papp-Kádár V, Nyíri K, Leveles I, Bendes AÁ, Zagyva I, Róna G, Pálinkás HL, Besztercei B, Ozohanics O, Vékey K, Liliom K, Tóth J, Vértessy BG.

Highly potent dUTPase inhibition by a bacterial repressor protein reveals a novel mechanism for gene expression control. Nucleic Acids Res. 2014 Oct 29;42(19):11912-20.

 

Muha V, Horváth A, Békési A, Pukáncsik M, Hodoscsek B, Merényi G, Róna G, Batki J, Kiss I, Jankovics F, Vilmos P, Erdélyi M, Vértessy BG.

Uracil-containing DNA in Drosophila: stability, stage-specific accumulation, and developmental

involvement.

PLoS Genet. 2012;8(6):e1002738.

 

Pécsi I, Szabó JE, Adams SD, Simon I, Sellers JR, Vértessy BG*, Tóth J*

(* corresponding authors)

Nucleotide pyrophosphatase employs a P-loop-like motif to enhance catalytic power

and NDP/NTP discrimination.

Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):14437-42.

 

Horváth A, Vértessy BG.

A one-step method for quantitative determination of uracil in DNA by real-time PCR.

Nucleic Acids Res. 2010 Nov;38(21):e196.

 

Vértessy BG, Tóth J.

Keeping uracil out of DNA: physiological role, structure and catalytic mechanism of dUTPases. Acc Chem Res. 2009 Jan 20;42(1):97-106.

Random Research Highlight

RRH_FEBS_J_importin.png

Contact

Genome Metabolism and Biostruct Laboratory

Budapest University of Technology, Ch building
Budapest
Szt. Gellért square 4.
HUNGARY
H-1111

RCNS HAS Institute of Enzymology
Budapest
Magyar tudosok korutja 2.
HUNGARY
H-1117